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There are 7 twelve-letter words containing 2E, 2F, I, O and T

AFFECTIONATEaffectionate adj. (Of a person) Having affection or warm regard; loving; fond.
affectionate adj. (Of an action, etc.) Characterised by or proceeding from affection; indicating love; tender.
affectionate adj. (Obsolete) Eager; passionate; strongly inclined toward something.
COEFFICIENTScoefficients n. Plural of coefficient.
coëfficients n. Plural of coëfficient.
COEFFICIENT n. any of the factors of a product considered in relation to a specific factor.
EFFECTUATIONeffectuation n. An act of effectuating.
EFFECTUATION n. the act of effectuating.
EFFRONTERIESeffronteries n. Plural of effrontery.
EFFRONTERY n. shameless boldness; presumptuousness.
EFFUSIOMETEReffusiometer n. A device that measures the rate of effusion of a gas.
EFFUSIOMETER n. an instrument for comparing the molecular weights of gases.
INTEROFFICESinteroffices v. Third-person singular simple present indicative form of interoffice.
NONEFFECTIVEnoneffective adj. Not effective.
noneffective adj. (Military) Not able to assume active duty.
noneffective n. A member of the military who is unable to assume active duty.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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