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There are 13 twelve-letter words containing 2E, 2F, I and 2N

DIFFERENCINGdifferencing v. Present participle of difference.
DIFFERENCE v. to make or perceive a difference between or in, also DIFFERENCY.
EFFEMINATINGeffeminating v. Present participle of effeminate.
EFFEMINATE v. (archaic) to render effeminate.
EFFEMINISINGeffeminising v. Present participle of effeminise.
EFFEMINISE v. (archaic) to make effeminate, also EFFEMINIZE.
EFFEMINIZINGeffeminizing v. Present participle of effeminize.
EFFEMINIZE v. (archaic) to make effeminate.
FENFLURAMINEfenfluramine n. An appetite suppressant used to treat obesity.
INDIFFERENCEindifference n. The state of being indifferent.
indifference n. Unbiased impartiality.
indifference n. Unemotional apathy.
INDIFFERENCYindifferency n. (Obsolete) Impartiality, fairness, disinterestedness.
indifferency n. (Obsolete) A lack of strong feeling; indifference.
INDIFFERENCY n. the state of being indifferent, also INDIFFERENCE.
INDIFFERENTSindifferents n. Plural of indifferent.
INDIFFERENT n. a person who is indifferent.
INEFFICIENCYinefficiency n. Lack of efficiency or effectiveness.
INEFFICIENCY n. the state of being inefficient.
INEFFICIENTSinefficients n. Plural of inefficient.
INEFFICIENT n. one who is not efficient.
NONEFFECTIVEnoneffective adj. Not effective.
noneffective adj. (Military) Not able to assume active duty.
noneffective n. A member of the military who is unable to assume active duty.
SNIFFINESSESsniffinesses n. Plural of sniffiness.
SNIFFINESS n. the state of being sniffy.
SNUFFINESSESSNUFFINESS n. the quality of being snuffy, soiled with snuff.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 45 words
  • Scrabble in French: 34 words
  • Scrabble in Spanish: no word
  • Scrabble in Italian: 44 words
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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