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There are 7 twelve-letter words containing 3E, H, 2M and S

HAEMATEMESEShaematemeses n. Plural of haematemesis.
HAEMATEMESIS n. vomiting of blood from the stomach, also HEMATEMESIS.
HAEMATEMESIShaematemesis n. (British spelling) Alternative spelling of hematemesis.
hæmatemesis n. Obsolete form of hematemesis.
HAEMATEMESIS n. vomiting of blood from the stomach, also HEMATEMESIS.
HOMOEOMERIEShomoeomeries n. Plural of homoeomery.
HOMOEOMERY n. the state of being homoeomeric, having all the somites alike, also HOMEOMERY.
METHENAMINESmethenamines n. Plural of methenamine.
METHENAMINE n. hexamethylenetetramine esp. when used in the form of an organic salt to treat urinary tract infections.
PENTHEMIMERSPENTHEMIMER n. a metrical group of two and a half feet.
SLEDGEHAMMERsledgehammer n. A hammer that consists of a large, heavy, broad and flat block of metal (the head) attached to a handle…
sledgehammer v. To strike with a sledgehammer.
SLEDGEHAMMER n. a large hammer used e.g. for breaking rocks.
THERMOMETERSthermometers n. Plural of thermometer.
THERMOMETER n. an instrument for determining temperature.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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