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There are 18 twelve-letter words containing 4E, O and 2S

AMELOGENESESamelogeneses n. Plural of amelogenesis.
AMELOGENESIS n. the production of enamel by ameloblasts.
CAENOGENESEScaenogeneses n. Plural of caenogenesis.
cænogeneses n. Plural of cænogenesis.
CAENOGENESIS n. the state where adaptations to the needs of the young stages develop early, and disappear in the adult stage, also CENOGENESIS, KAINOGENESIS, KENOGENESIS.
COENESTHESESCOENESTHESIS n. general awareness of one's own body.
ELECTORESSESelectoresses n. Plural of electoress.
ELECTORESS n. the wife or widow of an elector in the old German empire, also ELECTRESS.
HORSELEECHEShorseleeches n. Plural of horseleech.
horse-leeches n. Plural of horse-leech.
horse␣leeches n. Plural of horse leech.
HOUSEKEEPERShousekeepers n. Plural of housekeeper.
house␣keepers n. Plural of house keeper.
HOUSEKEEPER n. a woman employed to keep house.
NEUROGENESESNEUROGENESIS n. the production or generation of nerves.
OSTEOGENESESosteogeneses n. Plural of osteogenesis.
OSTEOGENESIS n. the production or formation of bone.
OVERSECRETESoversecretes v. Third-person singular simple present indicative form of oversecrete.
over-secretes v. Third-person singular simple present indicative form of over-secrete.
OVERSWEETENSoversweetens v. Third-person singular simple present indicative form of oversweeten.
OVERSWEETEN v. to sweeten to excess.
PAEDOGENESESPAEDOGENESIS n. reproduction by an infant or larval organism.
PETROGENESESpetrogeneses n. Plural of petrogenesis.
PETROGENESIS n. formation or development of rocks.
REMOTENESSESremotenesses n. Plural of remoteness.
REMOTENESS n. the state of being remote.
SCOREKEEPERSscorekeepers n. Plural of scorekeeper.
SCOREKEEPER n. one that keeps score.
SPEEDOMETERSspeedometers n. Plural of speedometer.
SPEEDOMETER n. an instrument for measuring speed.
SQUEEZEBOXESsqueezeboxes n. Plural of squeezebox.
squeeze␣boxes n. Plural of squeeze box.
STEREOMETERSstereometers n. Plural of stereometer.
STEREOMETER n. an instrument for measuring specific gravity.
STOREKEEPERSstorekeepers n. Plural of storekeeper.
STOREKEEPER n. one that has charge of supplies, as military stores.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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