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There are 7 ten-letter words containing E, 2I, 2M, P and R

EMPIRICISMempiricism n. (Medicine, now chiefly historical) Medicine as practised by an empiric, founded on mere experience…
empiricism n. (Philosophy) A doctrine which holds that the only or, at least, the most reliable source of human knowledge…
empiricism n. A pursuit of knowledge purely through experience, especially by means of observation and sometimes by experimentation.
EPIMERISMSEPIMERISM n. optical isomerism.
IMIPRAMINEimipramine n. (Pharmacology) A synthetic compound (trademark Tofranil) used to treat depression.
IMIPRAMINE n. an antidepressant drug also used in the treatment of enuresis.
IMPAIRMENTimpairment n. The result of being impaired.
impairment n. A deterioration or weakening.
impairment n. A disability or handicap.
METEMPIRICmetempiric adj. Of or relating to metempirics.
METEMPIRIC adj. transcending but associated with empirical knowledge, also METEMPIRICAL.
MISIMPROVEmisimprove v. (Transitive, archaic) To use for a bad purpose; to misuse.
MISIMPROVE v. to make worse by would-be improvement.
PERIMYSIUMperimysium n. (Anatomy) A layer of connective tissue which surrounds several muscle fibers into bundles.
PERIMYSIUM n. the connective tissue which surrounds and binds together muscle fibres.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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