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There are 3 ten-letter words containing 2E, I, P, R and 2U

EPINEURIUMepineurium n. (Anatomy) The connective tissue framework and sheath of a nerve which bind together the nerve bundles…
EPINEURIUM n. the connective tissue framework and sheath of a nerve.
PERRUQUIERperruquier n. A maker of perukes or wigs.
PERRUQUIER n. (French) a wigmaker.
PUERPERIUMpuerperium n. (Obstetrics) The period of time lasting around a month immediately following childbirth, when the mother’s…
PUERPERIUM n. (Latin) the condition immediately following childbirth.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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