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There are 10 ten-letter words containing 2E, I, 2N and 2P

EPINEPHRINepinephrin n. Alternative form of epinephrine.
EPINEPHRIN n. adrenalin, also EPINEPHRINE.
INAPPETENTinappetent adj. Lacking appetite.
INAPPETENT adj. lacking desire or appetite.
PENEPLAINSpeneplains n. Plural of peneplain.
PENEPLAIN n. a low gently, rolling landscape produced by long-continued erosion, also PENEPLANE.
PEPSINOGENpepsinogen n. (Biochemistry) A zymogen that is converted into pepsin by the hydrochloric acid in the stomach.
PEPSINOGEN n. a substance in the mucous membrane of the stomach which converts into pepsin in a slightly acid medium.
PERPENDINGperpending v. Present participle of perpend.
PERPEND v. to weigh in the mind; to consider carefully.
PINNIPEDESpinnipedes n. Plural of pinnipede.
PINNIPEDE n. a member of the Pinnipeda, seals, walruses, and other such sea mammals, also PINNIPED.
PORPENTINEporpentine n. (Archaic) Porcupine.
PORPENTINE n. (Shakespeare) a porcupine, also PORCUPINE.
PREOPENINGpreopening adj. Occurring before or in anticipation of an opening.
PREOPENING adj. taking place before an opening.
PREPENSINGprepensing v. Present participle of prepense.
PREPENSE v. (Spenser) to consider.
TUPPENNIEStuppennies n. Plural of tuppenny.
TUPPENNY n. two pennies, also TWOPENNY.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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