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There are 12 words containing 2E, 2M, R and X

EXTREMUMextremum n. (Mathematics) A point, or value, which is a maximum or a minimum.
EXTREMUM n. (Latin) a maximum or minimum of a mathematical function.
EXTREMISMextremism n. Extreme ideas or actions, primarily in politics or religion.
EXTREMISM n. the taking of an extreme position.
EXTREMUMSextremums n. Plural of extremum.
EXTREMUM n. (Latin) a maximum or minimum of a mathematical function.
EXTREMISMSextremisms n. Plural of extremism.
EXTREMISM n. the taking of an extreme position.
HEXAMERISMhexamerism n. Six-part radial symmetry.
HEXAMERISM n. the state of being hexamerous.
EXCREMENTUMEXCREMENTUM n. (Latin) waste material or rubbish.
HEXAMERISMSHEXAMERISM n. the state of being hexamerous.
XERANTHEMUMxeranthemum n. Any of the genus Xeranthemum of flowering plants native to Southern Europe.
XERANTHEMUM n. any plant of the Xeranthemum genus of plants of southern Europe, belonging to the thistle family.
XERANTHEMUMSxeranthemums n. Plural of xeranthemum.
XERANTHEMUM n. any plant of the Xeranthemum genus of plants of southern Europe, belonging to the thistle family.
AXISYMMETRIESaxisymmetries n. Plural of axisymmetry.
AXISYMMETRY n. the state of being axisymmetric.
COMPLEXOMETRICcomplexometric adj. (Chemistry) Describing a form of titration in which the titrant forms a complex (usually coloured) with the analyte.
complexometric adj. (Chemistry) Describing any indicator that is used in such titrations.
COMPLEXOMETRIC adj. as in complexometric indicator, a dye that undergoes a definite color change in presence of specific metal ions.
EXPERIMENTALISMexperimentalism n. An experimental practice or tendency, especially in the arts.
experimentalism n. (Philosophy) An empirical or pragmatic approach which emphasizes the importance of experimentation.
EXPERIMENTALISM n. reliance on or advocacy of experimental or empirical principles and procedures.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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