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There is only one eight-letter word containing 2E, I, M, P and U

PERINEUMperineum n. (Anatomy) The region between the human genitalia, especially the scrotum, and anus. The male perineum…
PERINEUM n. the lower part of the body between the genital organs and the anus, also PERINAEUM.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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