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There are 5 seven-letter words containing 2E, M, P, R and U

PERFUMEperfume n. A pleasant smell; the scent, odor, or odoriferous particles emitted from a sweet-smelling substance; a pleasant odor.
perfume n. (Cosmetics) A substance created to provide a pleasant smell or one which emits an agreeable odor.
perfume v. (Transitive) To apply perfume to; to fill or impregnate with a perfume; to scent.
PERMUTEpermute v. (Transitive) change the order of.
permute v. (Transitive, mathematics) make a permutation of.
PERMUTE v. to alter the order, sequence, or arrangement of, also PERMUTATE.
PREMUNEpremune adj. (Medicine) Immune to a disease through having had it before.
PREMUNE adj. resistant to a disease.
PRESUMEpresume v. (Transitive) With infinitive object: to be so presumptuous as (to do something) without proper authority…
presume v. (Transitive, now rare) To perform, do (something) without authority; to lay claim to without permission.
presume v. (Transitive) To assume or suggest to be true (without proof); to take for granted, to suppose.
SUPREMEsupreme adj. Dominant, having power over all others.
supreme adj. (Sometimes postpositive) Greatest, most excellent, extreme, most superior, highest, or utmost.
supreme adj. (Botany) Situated at the highest part or point.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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