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There are 18 seven-letter words containing 2E, M, P, R and S

AMPERESamperes n. Plural of ampere.
ampères n. Plural of ampère.
AMPERE n. (French) a unit of electric current strength.
DEPERMSdeperms v. Third-person singular simple present indicative form of deperm.
deperms n. Plural of deperm.
DEPERM v. to demagnetize (a ship or submarine) to protect it from magnetic detection.
EMPARESEMPARE v. (Spenser) to become worse, also EMPAIRE.
EMPIRESempires n. Plural of empire.
EMPIRE n. a dominion of peoples and nations under the same power.
EMPRESSempress n. The female monarch (ruler) of an empire.
empress n. The wife or widow of an emperor or equated ruler.
empress n. (Tarot) The third trump or major arcana card of most tarot decks.
EMPRISEemprise n. (Archaic) An enterprise or endeavor, especially a quest or adventure.
emprise n. (Archaic) The qualities which prompt one to undertake difficult and dangerous exploits; chivalric prowess.
emprise v. (Obsolete) To undertake.
EPIMERSepimers n. Plural of epimer.
EPIMER n. a type of sugar compound.
IMPRESEimprese n. A heraldic device; an impresa.
IMPRESE n. (Italian) an emblem with a motto, also IMPRESA, IMPRESSE.
KEMPERSkempers n. Plural of kemper.
KEMPER n. a champion.
PERMIESpermies n. Plural of permie.
PERMIE n. a permanent worker, as opposed to a temp.
PREMEDSpremeds n. Plural of premed.
PREMED n. a student preparing for the study of medicine, also PREMEDIC.
PREMIESpremies n. Plural of premie.
premies n. Plural of premy.
PREMY n. (US slang) a premature baby, also PREEMIE, PREM, PREMIE.
PREMISEpremise n. A proposition antecedently supposed or proved; something previously stated or assumed as the basis of…
premise n. (Logic) Any of the first propositions of a syllogism, from which the conclusion is deduced.
premise n. (Usually in the plural, law) Matters previously stated or set forth; especially, that part in the beginning…
PRESUMEpresume v. (Transitive) With infinitive object: to be so presumptuous as (to do something) without proper authority…
presume v. (Transitive, now rare) To perform, do (something) without authority; to lay claim to without permission.
presume v. (Transitive) To assume or suggest to be true (without proof); to take for granted, to suppose.
SEMPLERSEMPLE adj. (Scots) of humble birth.
SPIREMEspireme n. (Dated, biochemistry) the tangled mass of strands of chromatin seen in the early stages of mitosis…
SPIREME n. a filament forming part of a cell nucleus, also SPIREM.
SUPREMEsupreme adj. Dominant, having power over all others.
supreme adj. (Sometimes postpositive) Greatest, most excellent, extreme, most superior, highest, or utmost.
supreme adj. (Botany) Situated at the highest part or point.
TEMPERStempers n. Plural of temper.
tempers v. Third-person singular simple present indicative form of temper.
TEMPER v. to moderate by adding a counterbalancing agent.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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