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There are 16 seven-letter words containing 2E, I, M, P and S

EMPIRESempires n. Plural of empire.
EMPIRE n. a dominion of peoples and nations under the same power.
EMPRISEemprise n. (Archaic) An enterprise or endeavor, especially a quest or adventure.
emprise n. (Archaic) The qualities which prompt one to undertake difficult and dangerous exploits; chivalric prowess.
emprise v. (Obsolete) To undertake.
EMPTIESempties v. Third-person singular simple present indicative form of empty.
empties n. Plural of empty.
EMPTY v. to remove the contents of.
EPIMERSepimers n. Plural of epimer.
EPIMER n. a type of sugar compound.
EPISOMEepisome n. (Cytology) A segment of DNA that can exist and replicate either autonomously in the cytoplasm or as…
episome n. Synonym of epitheca.
EPISOME n. a genetically active particle found in bacteria.
HEMPIEShempies n. Plural of hempie.
hempies n. Plural of hempy.
HEMPY n. a rogue, a tomboy.
IMPEDESimpedes v. Third-person singular simple present indicative form of impede.
IMPEDE v. to retard by obstructing.
IMPHEESimphees n. Plural of imphee.
IMPHEE n. (Zulu) any of several southern African varieties of sorghum.
IMPRESEimprese n. A heraldic device; an impresa.
IMPRESE n. (Italian) an emblem with a motto, also IMPRESA, IMPRESSE.
MISKEEPmiskeep v. (Transitive) To keep ill or wrongly.
MISKEEP v. to keep wrongly.
PERMIESpermies n. Plural of permie.
PERMIE n. a permanent worker, as opposed to a temp.
PREMIESpremies n. Plural of premie.
premies n. Plural of premy.
PREMY n. (US slang) a premature baby, also PREEMIE, PREM, PREMIE.
PREMISEpremise n. A proposition antecedently supposed or proved; something previously stated or assumed as the basis of…
premise n. (Logic) Any of the first propositions of a syllogism, from which the conclusion is deduced.
premise n. (Usually in the plural, law) Matters previously stated or set forth; especially, that part in the beginning…
SEMIPEDsemiped n. (Poetry) Half of a metrical foot.
SEMIPED n. a half foot.
SEPTIMEseptime n. (Fencing) The seventh defensive position, with the sword hand held at waist height, and the tip of the…
SEPTIME n. the seventh parrying position in fencing.
SPIREMEspireme n. (Dated, biochemistry) the tangled mass of strands of chromatin seen in the early stages of mitosis…
SPIREME n. a filament forming part of a cell nucleus, also SPIREM.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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