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There are 3 six-letter words containing 2E, I, M and 2S

EMESISemesis n. (Pathology) The act or process of vomiting.
EMESIS n. (Greek) the act of vomiting.
MISSEEmissee v. (Transitive) To see incorrectly; to misperceive visually; take a wrong view of; see in a false or distorted light.
missee v. (Intransitive) To take a wrong, false, or distorted view; fail to see accurately.
missee n. Archaic form of missy (“miss; young lady”).
SEMIESSEMIE n. at Scottish universities, a second-year student.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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