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There are 10 twelve-letter words containing E, 2N, O, P and X

EXPANSIONARYexpansionary adj. That promotes or exhibits expansion; expansionist.
EXPANSIONARY adj. tending toward expansion.
EXPANSIONISMexpansionism n. The policy, of a nation, of expanding its territory or its economic influence.
EXPANSIONISM n. a policy or practice of expansion and esp. of territorial expansion by a nation.
EXPANSIONISTexpansionist adj. Of or pertaining to expansionism.
expansionist n. An advocate of expansionism.
EXPANSIONIST n. an advocate of expansionism.
EXPLANATIONSexplanations n. Plural of explanation.
EXPLANATION n. the act of explaining.
EXPLANTATIONexplantation n. The act of explanting.
EXPLANTATION n. the act of explanting.
EXPONENTIALSexponentials n. Plural of exponential.
EXPONENTIAL n. an exponential function.
EXPUGNATIONSexpugnations n. Plural of expugnation.
EXPUGNATION n. the act of expugning.
HYPOXANTHINEhypoxanthine n. (Organic chemistry) A bicyclic heterocycle, 3,7-dihydropurin-6-one, that is an intermediate in the biosynthesis…
HYPOXANTHINE n. a purine base found in plant and animal tissues that yields xanthine on oxidation.
NONEXPLOSIVEnonexplosive adj. Not explosive; unable to explode.
NONEXPLOSIVE adj. not explosive.
XANTHOPTERINxanthopterin n. A yellow crystalline solid that occurs mainly in the wings of butterflies and in the urine of mammals…
XANTHOPTERIN n. a yellow pigment obtainable from the wings of yellow butterflies and the urine of mammals, also XANTHOPTERINE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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