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There are 11 twelve-letter words containing 2E, G, M, P and U

GRUMPINESSESgrumpinesses n. Plural of grumpiness.
GRUMPINESS n. the state of being grumpy.
MAGNETOPAUSEmagnetopause n. The boundary between the Earth’s magnetosphere and the sun’s plasma.
MAGNETOPAUSE n. the outer boundary of a magnetosphere.
MUGWUMPERIESMUGWUMPERY n. the acts and views of a mugwump, a bolter from the Republican party in 1884; a political independent.
MUMBLETYPEGSMUMBLETYPEG n. a game of throwing knives to make them stick in the ground.
PERGAMENEOUSpergameneous adj. Parchment-like.
PERGAMENEOUS adj. parchment-like, also PERGAMENTACEOUS.
PHLEGMAGOGUEphlegmagogue n. (Obsolete) Any medicine supposed to expel phlegm.
PHLEGMAGOGUE n. a phlegm-expelling drug.
PREJUDGEMENTprejudgement n. Alternative spelling of prejudgment.
PREJUDGEMENT n. the act of prejudging, also PREJUDGMENT.
PREJUDGMENTSprejudgments n. Plural of prejudgment.
PREJUDGMENT n. the act of prejudging, also PREJUDGEMENT.
PREMEASURINGpremeasuring v. Present participle of premeasure.
PREMEASURE v. to measure in advance.
PRENUMBERINGprenumbering v. Present participle of prenumber.
PRENUMBER v. to number in advance.
PSEUDIMAGOESpseudimagoes n. Plural of pseudimago.
PSEUDIMAGO n. a stage in the development of certain insects, such as the May flies, intermediate between the pupa and imago.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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