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There are 5 twelve-letter words containing 2E, F, 2N and P

FLUPHENAZINEfluphenazine n. (Pharmacology) An antipsychotic drug of the phenothiazine class, which can be administered orally or by injection.
FLUPHENAZINE n. a tranquilizer used esp. in the form of its hydrochloride.
FORESPENDINGforespending v. Present participle of forespend.
FORESPEND v. to wear out physically, also FORSPEND.
FRIPONNERIESFRIPONNERIE n. (French) knavery.
NONPERFORMERnonperformer n. Someone who is not a performer.
NONPERFORMER n. one who is not a performer.
UNPERFECTIONunperfection n. (Obsolete or nonstandard) Want of perfection; imperfection.
UNPERFECTION n. (obsolete) imperfection.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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