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There are 12 ten-letter words containing E, 2M, 2O and U

HUMOURSOMEhumoursome adj. (Archaic) Liable to humours or moods; fickle; ill-tempered.
HUMOURSOME adj. capricious, petulant, also HUMORSOME.
MONOMEROUSmonomerous adj. (Botany) Composed of solitary parts, as a flower with one sepal, one petal, one stamen, and one pistil.
monomerous adj. (Zoology) Having only one joint; said of the foot of certain insects.
MONOMEROUS adj. of flowers, having whorls consisting of only one member.
MUSHROOMEDmushroomed v. Simple past tense and past participle of mushroom.
MUSHROOM v. to grow or spread rapidly.
MUSHROOMERmushroomer n. One who gathers (picks or hunts) mushrooms.
MUSHROOMER n. something that mushrooms, expands rapidly.
POLEMONIUMpolemonium n. Any of the genus Polemonium of gamopetalous perennial herbs.
Polemonium prop.n. A taxonomic genus within the family Polemoniaceae – Jacob’s ladder and related flowering plants.
POLEMONIUM n. a genus of gamopetalous perennial herbs, including the Jacob's ladder and the Greek valerian.
POMOERIUMSPOMOERIUM n. (Latin) an open space around a town within the walls.
POMPELMOUSpompelmous n. (Obsolete) Alternative form of pampelmoes: a pomelo; a grapefruit.
POMPELMOUS n. (Dutch) the shaddock or grapefruit, also PAMPELMOOSE, PAMPELMOUSE, POMELO, POMPELMOOSE, POMPELMOUSE, POMPELO, PUMELO, PUMMELO.
PROOEMIUMSproœmiums n. Plural of proœmium.
PROOEMIUM n. a preface, also PROEM, PROOEMION.
STOMODAEUMstomodaeum n. Alternative spelling of stomodeum.
stomodæum n. Obsolete form of stomodeum.
STOMODAEUM n. in embryology, the invagination that forms the anterior part of the digestive tract, also STOMODEUM.
STOMODEUMSSTOMODEUM n. an embryonic oral cavity.
SUMMERWOODsummerwood n. The wood in a tree’s growth ring formed later in the growing season, when growth is less rapid.
SUMMERWOOD n. wood with smaller and thicker-walled cells than springwood.
UNCOMMONERuncommoner adj. Comparative form of uncommon: more uncommon.
UNCOMMON adj. not common.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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