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There are 14 ten-letter words containing E, 2I, 2M and P

AMPHIMIXESamphimixes n. Plural of amphimixis.
AMPHIMIXIS n. interbreeding; intermixing of two individuals' genetic matter.
EMPIRICISMempiricism n. (Medicine, now chiefly historical) Medicine as practised by an empiric, founded on mere experience…
empiricism n. (Philosophy) A doctrine which holds that the only or, at least, the most reliable source of human knowledge…
empiricism n. A pursuit of knowledge purely through experience, especially by means of observation and sometimes by experimentation.
EPIMERISMSEPIMERISM n. optical isomerism.
IMIPRAMINEimipramine n. (Pharmacology) A synthetic compound (trademark Tofranil) used to treat depression.
IMIPRAMINE n. an antidepressant drug also used in the treatment of enuresis.
IMPAIRMENTimpairment n. The result of being impaired.
impairment n. A deterioration or weakening.
impairment n. A disability or handicap.
IMPEDIMENTimpediment n. A hindrance; that which impedes or obstructs progress.
impediment n. A disability, especially one affecting the hearing or speech.
impediment n. (Chiefly in the plural) Baggage, especially that of an army; impedimenta.
MEDIUMSHIPmediumship n. (Parapsychology) The state of being a medium (psychic conduit); purported ability to mediate communication…
MEDIUMSHIP n. being a medium.
MEPHITISMSmephitisms n. Plural of mephitism.
MEPHITISM n. poisoning by mephitis.
METEMPIRICmetempiric adj. Of or relating to metempirics.
METEMPIRIC adj. transcending but associated with empirical knowledge, also METEMPIRICAL.
MIDSHIPMENmidshipmen n. Plural of midshipman.
MIDSHIPMAN n. formerly, the title of a young officer (originally quartered amidships) entering the navy.
MISIMPROVEmisimprove v. (Transitive, archaic) To use for a bad purpose; to misuse.
MISIMPROVE v. to make worse by would-be improvement.
PERIMYSIUMperimysium n. (Anatomy) A layer of connective tissue which surrounds several muscle fibers into bundles.
PERIMYSIUM n. the connective tissue which surrounds and binds together muscle fibres.
PESSIMISMSpessimisms n. Plural of pessimism.
PESSIMISM n. a tendency to look on the dark side of things.
PIMPMOBILEpimpmobile n. (Slang) An extravagantly large or ornate automobile, presumably suitable for a pimp.
PIMPMOBILE n. a car used by a pimp.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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