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There are 3 ten-letter words containing 2E, 2M, T and X

EXTREMISMSextremisms n. Plural of extremism.
EXTREMISM n. the taking of an extreme position.
METAXYLEMSmetaxylems n. Plural of metaxylem.
METAXYLEM n. a part of the primary xylem.
MYXOMYCETEmyxomycete n. Any protozoan of the phylum Myxomycota; the slime molds.
MYXOMYCETE n. slime mould.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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