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There are 3 ten-letter words containing 2E, I, 2M and X

EXTREMISMSextremisms n. Plural of extremism.
EXTREMISM n. the taking of an extreme position.
HEXAMERISMhexamerism n. Six-part radial symmetry.
HEXAMERISM n. the state of being hexamerous.
MYXOEDEMICmyxoedemic adj. Alternative form of myxedemic.
MYXOEDEMIC adj. relating to myxoedema, a skin disease, also MYXEDEMIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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