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There are 18 eight-letter words containing 2E, N, P and X

CINEPLEXcineplex n. (US) A cinema having multiple theatres (showing rooms).
CINEPLEX n. a multiple cinema complex.
EXPANDEDexpanded v. Simple past tense and past participle of expand.
EXPAND v. to increase in size or volume.
EXPANDERexpander n. One who expands; something that expands.
expander n. (Dentistry) A device used to widen the upper jaw so that the bottom and upper teeth will fit together…
expander n. (Graphical user interface) A control that expands to show more options or commands, keeping them hidden until needed.
EXPANSESexpanses n. Plural of expanse.
EXPANSE n. a wide area or extent.
EXPENDEDexpended v. Simple past tense and past participle of expend.
expended adj. Spent; used up; exhausted.
EXPEND v. to consume in any way.
EXPENDERexpender n. One who, or that which, expends.
EXPENDER n. one who expends.
EXPENSEDexpensed v. Simple past tense and past participle of expense.
EXPENSE v. to charge with costs.
EXPENSESexpenses n. Plural of expense.
expenses v. Third-person singular simple present indicative form of expense.
EXPENSE v. to charge with costs.
EXPONENTexponent n. One who expounds, represents or advocates.
exponent n. (Mathematics) The number by which a value (called the base) is said to be raised to a power in exponentiation…
exponent n. (Mathematics, obsolete) The degree to which the root of a radicand is found, for example, the 2 in 2]𝑟=𝑏.
EXPUGNEDexpugned v. Simple past tense and past participle of expugn.
EXPUGN v. to take by storm.
EXPUNGEDexpunged v. Simple past tense and past participle of expunge.
EXPUNGE v. to delete.
EXPUNGERexpunger n. One who expunges.
EXPUNGER n. one who expunges.
EXPUNGESexpunges v. Third-person singular simple present indicative form of expunge.
EXPUNGE v. to delete.
INEXPERTinexpert adj. Inept or unskilled; not of expert ability or quality.
inexpert n. An inept or unskilled person.
INEXPERT adj. not expert, also UNEXPERT.
PHENIXESphenixes n. Plural of phenix.
PHENIX n. a bird fabled to exist single, to be consumed by fire by its own act, and to rise again from its ashes, also PHOENIX.
PYROXENEpyroxene n. (Mineralogy) Any of a group of crystalline minerals containing silicates of iron, magnesium and calcium.
PYROXENE n. any of a group of minerals common in igneous rocks.
SIXPENCEsixpence n. (Obsolete, Britain, uncountable) The value of six old pence; half of a shilling; or one-fortieth of a pound sterling.
sixpence n. (Historical) A former British coin worth sixpence, first minted in 1551.
SIXPENCE n. an obsolete British coin worth six pence.
UNEXPERTunexpert adj. Synonym of inexpert.
UNEXPERT adj. not expert, also INEXPERT.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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