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There are 13 eight-letter words containing 2E, N, O and X

AXONEMESaxonemes n. Plural of axoneme.
AXONEME n. a central strand of a locomotor organelle such as a cilium or flagellum.
COEXTENDcoextend v. (Transitive, intransitive) To extend along with another.
COEXTEND v. to extend equally in space or time.
CONVEXEDconvexed adj. Made convex; protuberant in a spherical form.
CONVEX v. to make convex.
CONVEXESconvexes n. Plural of convex.
CONVEX v. to make convex.
EXERTIONexertion n. An expenditure of physical or mental effort.
EXERTION n. the act of exerting.
EXOCRINEexocrine adj. Producing external secretions that are released through a duct#Noun.
exocrine adj. Pertaining to the exocrine glands or their secretions.
exocrine n. The secretion of an exocrine gland.
EXOGENICexogenic adj. (Geology) Originating on or above the surface of the earth; exogenetic.
exogenic adj. Existing or arising outside of a system.
exogenic adj. (Medicine, dermatology) Relating to the exogen growth phase.
EXONEREEexoneree n. One who is exonerated.
EXONEREE n. a person who is proven not guilty of a crime.
EXPONENTexponent n. One who expounds, represents or advocates.
exponent n. (Mathematics) The number by which a value (called the base) is said to be raised to a power in exponentiation…
exponent n. (Mathematics, obsolete) The degree to which the root of a radicand is found, for example, the 2 in 2]𝑟=𝑏.
EXTENSORextensor n. (Anatomy) A muscle whose contraction extends or straightens a limb or body part.
EXTENSOR n. a muscle that extends a limb.
PYROXENEpyroxene n. (Mineralogy) Any of a group of crystalline minerals containing silicates of iron, magnesium and calcium.
PYROXENE n. any of a group of minerals common in igneous rocks.
XENOGENYxenogeny n. Xenogenesis.
XENOGENY n. the production of offspring totally different from the parent.
XENOTIMExenotime n. (Mineralogy) A yellow-brown mineral, yttrium phosphate (YPO4).
XENOTIME n. (Greek) a phosphate of yttrium occurring in yellowish-brown tetragonal crystals.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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