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There are 17 eight-letter words containing 2E, M, S and X

AXONEMESaxonemes n. Plural of axoneme.
AXONEME n. a central strand of a locomotor organelle such as a cilium or flagellum.
BEMBEXESBEMBEX n. (Greek) a noisy sand-wasp, also BEMBIX.
BEMBIXESBEMBIX n. (Greek) a noisy sand-wasp, also BEMBEX.
EXAMINESexamines v. Third-person singular simple present indicative form of examine.
EXAMINE v. to inspect.
EXAMPLESexamples n. Plural of example.
examples v. Third-person singular simple present indicative form of example.
EXAMPLE v. to illustrate, show by representation.
EXCIMERSexcimers n. Plural of excimer.
EXCIMER n. a dimer above the ground state.
EXEMPLESexemples n. Plural of exemple.
EXEMPLE n. (French) an example or model.
EXHUMERSexhumers n. Plural of exhumer.
EXHUMER n. someone who exhumes.
EXODERMSexoderms n. Plural of exoderm.
EXODERM n. the external layer of an embryo, also ECTODERM, EPIBLAST.
EXOMISESEXOMIS n. (Greek) a Roman sleeveless garment, also EXOMION.
EXOSMOSEexosmose n. Archaic form of exosmosis.
EXOSMOSE n. osmosis outwards, i.e. away from the solution, also EXOSMOSIS.
EXPOSOMEexposome n. A measure of the effects of life-long environmental exposures on health.
EXPOSOME n. a collection of environmental factors, such as stress and diet, to which an individual is exposed and which can have an effect on health.
EXTREMESextremes n. Plural of extreme.
EXTREME n. the highest degree.
IMPLEXESimplexes n. Plural of implex.
IMPLEX n. (Latin) a muscle attachment in jointed creatures like centipedes.
MEATAXESmeataxes n. Plural of meataxe.
meat␣axes n. Plural of meat axe.
MEATAXE n. a meat cleaver.
PREMIXESpremixes n. Plural of premix.
PREMIX v. to mix before use.
REMIXERSremixers n. Plural of remixer.
REMIXER n. one that remixes (a recording).

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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