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There are 2 five-letter words containing 2E, L, P and R

LEPERleper n. A person who has leprosy, a person suffering from Hansen’s disease.
leper n. (Figurative) Synonym of outcast: A person who is shunned, a pariah.
leper v. (Now rare) To afflict with leprosy.
REPELrepel v. (Transitive, now rare) To turn (someone) away from a privilege, right, job, etc.
repel v. (Transitive) To reject, put off (A request, demand etc.).
repel v. (Transitive) To ward off (A malignant influence, attack etc.).

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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