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There are 12 twelve-letter words containing E, M and 3U

EQUINUMEROUSequinumerous adj. (Mathematics) Having equal cardinality.
EQUINUMEROUS adj. having the same number of members.
GUBERNACULUMgubernaculum n. A part or structure that serves as a guide…
GUBERNACULUM n. in mammals, the cord supporting the testicles in the scrotal sac.
MUCOPURULENTmucopurulent adj. (Medicine) Characterized by mucus and pus.
MUCOPURULENT adj. containing a mixture of mucus and pus.
MULTUNGULATEmultungulate adj. Having many hoofs.
multungulate n. Any mammal with many hoofs.
MULTUNGULATE adj. having the hoof divided into more than two parts.
MUSCULATURESmusculatures n. Plural of musculature.
MUSCULATURE n. the muscles of all or a part of the animal body.
NEUROHUMOURSneurohumours n. Plural of neurohumour.
NEUROHUMOUR n. a neurohormone, esp. a neurotransmitter, also NEUROHUMOR.
PLUMULACEOUSplumulaceous adj. (Zoology, ornithology) Downy; bearing down.
PLUMULACEOUS adj. of or like plumulae, little feathers.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
QUINQUENNIUMquinquennium n. A period of five years.
QUINQUENNIUM n. a period of five years, also QUINQUENNIAD.
SUBOPERCULUMsuboperculum n. (Anatomy) The lower opercular bone in fishes.
SUBOPERCULUM n. in fishes, a bone below and partly behind the gill cover.
SUPERNACULUMsupernaculum adv. (Obsolete) According to the rules of an old drinking game in which the drinker upturned the empty cup…
supernaculum adv. To the last drop, to the bottom.
supernaculum n. (Obsolete) Excellent wine that one would wish to drink to the last drop.
UNGUENTARIUMunguentarium n. A small bottle used to store balms or scented oils.
UNGUENTARIUM n. a vessel for holding unguents.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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