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There are 12 twelve-letter words containing 2E, 2F and M

AFFORCEMENTSafforcements n. Plural of afforcement.
AFFORCEMENT n. the act of afforcing, strengthening a jury by adding skilled people.
COFFEEMAKERScoffeemakers n. Plural of coffeemaker.
coffee-makers n. Plural of coffee-maker.
coffee␣makers n. Plural of coffee maker.
EFFEMINACIESeffeminacies n. Plural of effeminacy.
EFFEMINACY n. the quality of being effeminate.
EFFEMINATELYeffeminately adv. In an effeminate manner.
EFFEMINATE adv. womanish.
EFFEMINATINGeffeminating v. Present participle of effeminate.
EFFEMINATE v. (archaic) to render effeminate.
EFFEMINISINGeffeminising v. Present participle of effeminise.
EFFEMINISE v. (archaic) to make effeminate, also EFFEMINIZE.
EFFEMINIZINGeffeminizing v. Present participle of effeminize.
EFFEMINIZE v. (archaic) to make effeminate.
EFFUSIOMETEReffusiometer n. A device that measures the rate of effusion of a gas.
EFFUSIOMETER n. an instrument for comparing the molecular weights of gases.
ENFEOFFMENTSenfeoffments n. Plural of enfeoffment.
ENFEOFFMENT n. the act of enfeoffing.
FENFLURAMINEfenfluramine n. An appetite suppressant used to treat obesity.
FLAMEPROOFEDflameproofed v. Simple past tense and past participle of flameproof.
FLAMEPROOF v. to make resistant to damage or burning on contact with flame.
FLAMEPROOFERflameproofer n. Any substance used for flameproofing.
FLAMEPROOFER n. one who flameproofs.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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