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There are 16 ten-letter words containing 2E, P, X and Y

EPICALYXESepicalyxes n. Plural of epicalyx.
EPICALYX n. a set of bracts resembling a calyx.
EXPECTABLYexpectably adv. In an expectable manner.
EXPECTABLE adv. that may be expected.
EXPECTANCYexpectancy n. Expectation or anticipation; the state of expecting something.
expectancy n. The state of being expected. (The addition of quotations indicative of this usage is being sought:)
expectancy n. (Law) Future interest as to possession or enjoyment.
EXPECTEDLYexpectedly adv. In an expected way; as expected; predictably.
EXPECTED adv. EXPECT, to anticipate.
EXPEDIENCYexpediency n. (Uncountable) The quality of being fit or suitable to effect some desired end or the purpose intended;…
expediency n. (Uncountable) Pursuit of the course of action that brings the desired effect even if it is unjust or unprincipled.
expediency n. (Obsolete) Haste; dispatch.
EXPEDITELYexpeditely adv. In an expedite manner; expeditiously.
EXPEDITE adv. expeditious.
EXPENDABLYEXPENDABLE adv. able to be expended.
EXPRESSWAYexpressway n. (US, regional) A divided highway, especially one whose intersections and direct access to adjacent properties…
expressway n. (Canada, parts of the US, Malaysia, Singapore) A road built to freeway standards.
expressway n. (UK, New Zealand) A road built for high speed traffic, but not up to motorway standards or designated a motorway.
HYPEROXIDEhyperoxide n. (Inorganic chemistry) Any oxide that has a higher than normal ratio of oxygen to metal.
HYPEROXIDE adj. a compound containing a relatively large proportion of oxygen.
HYPERTEXTShypertexts n. Plural of hypertext.
HYPERTEXT n. computer software and hardware that allows users to create, store, and view text and move between related items easily and in a nonsequential way.
INEXPERTLYinexpertly adv. In an inexpert manner.
INEXPERT adv. one who lacks specific skills, also NONEXPERT.
NEPHROPEXYnephropexy n. (Surgery) suspension or fixation of the kidney.
NEPHROPEXY n. the fixation of a floating kidney.
PERPLEXITYperplexity n. The state or quality of being perplexed; puzzled or confused.
perplexity n. Something that perplexes.
perplexity n. In information theory, a measurement of how well a probability distribution or model predicts a sample.
PLEXIMETRYpleximetry n. The use of the pleximeter.
PLEXIMETRY n. the use of a pleximeter, a small, hard, elastic plate, as of ivory, bone, or rubber, placed in contact with body to receive the blow, in examination by mediate percussion.
PYROXENITEpyroxenite n. (Geology) A heavy, dark igneous rock consisting mostly of pyroxene minerals with smaller amounts of…
PYROXENITE n. a rock consisting essentially of pyroxene.
XEROPHYTESxerophytes n. Plural of xerophyte.
XEROPHYTE n. a plant thriving in desert conditions.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 53 words
  • Scrabble in French: 16 words
  • Scrabble in Spanish: 6 words
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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