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There are 4 five-letter words containing E, 2P and U

POUPEPOUPE v. (obsolete) to befool, to cozen, also POOP.
PUPAEpupae n. Plural of pupa.
pupæ n. (Obsolete) plural of pupa.
PUPA n. (Latin) an insect in the stage between larva and imago.
UPPEDupped v. Simple past tense and past participle of up.
UP v. to raise.
UPPERupper adj. At a higher level, rank or position.
upper adj. Situated on higher ground, further inland, or more northerly.
upper adj. (Geology, of strata or geological time periods) younger, more recent.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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