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There are 6 five-letter words containing E, I, O and P

LOIPEloipe n. A cross-country ski trail.
LOIPE n. (Danish) a track for cross-country skiing.
OPINEopine v. (Intransitive, transitive) To have or express an opinion; to state as an opinion; to suppose, consider (that).
opine v. (Intransitive) To give one’s formal opinion (on or upon something).
opine n. (Biochemistry) Any of a class of organic compounds, derived from amino acids, found in some plant tumours.
PIEZOpiezo adj. Of or relating to a kind of ignition, used in portable camping stoves etc., where pressing a button…
piezo- pref. Piezoelectricity or other effects of mechanical stress or pressure.
PIEZO adj. (short for) piezoelectric, relating to electric current generated by compression of crystals.
PIOYEPIOYE n. (Scots) a homemade firework, also PEEOY, PIOY.
POISEpoise n. A state of balance, equilibrium or stability.
poise n. Composure; freedom from embarrassment or affectation.
poise n. Mien; bearing or deportment of the head or body.
POKIEpokie n. (Australia, New Zealand, slang, chiefly in the plural) A poker machine.
pokie n. (Informal) Any of several species of arboreal tarantula in the genus Poecilotheria.
POKIE n. a poker machine.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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