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There are 12 five-letter words containing 2E, I and N

AINEEAINEE adj. (French) (of a female) elder, senior.
DIENEdiene n. (Organic chemistry) An organic compound, especially a hydrocarbon, containing two double bonds.
-diene suff. (Organic chemistry) An unsaturated hydrocarbon with two double bonds; a diene.
-diene suff. (Organic chemistry) A polymer of such a diene.
EIGNEeigne adj. (Law, obsolete) eldest; firstborn.
eigne adj. (Law, obsolete) entailed; belonging to the eldest son.
EIGNE adj. (archaic) first born.
EXINEexine n. (Botany, palynology) the outer layer of a pollen grain or spore; the exosporium.
EXINE n. the outer layer of some spores, also EXTINE.
EZINEezine n. Alternative spelling of e-zine.
e-zine n. (Computing) A magazine published in electronic form, especially on the World Wide Web.
EZINE n. a magazine available only in electronic form, for example on the internet.
GENIEgenie n. (Islam) A jinn, a being descended from the jann, normally invisible to the human eye, but who may also…
genie n. (Mythology) A fictional magical being that is typically bound to obey the commands of a mortal possessing…
Genie prop.n. A male given name Diminutive of Eugene and pet form of Gene.
NEIVENEIVE n. (archaic) the fist, also NEAFE, NEAFFE, NEIF, NIEF, NIEVE.
NEWIEnewie n. (Informal) Something newly released, such as a song or film.
NEWIE n. (Australian slang) a newcomer.
NIECEniece n. A daughter of one’s sibling, brother-in-law, or sister-in-law; either the daughter of one’s brother…
niece n. A daughter of one’s cousin or cousin-in-law.
Niece prop.n. A surname.
NIEVEnieve n. Variant form of nief.
NIEVE n. (archaic) the fist, also NEAFE, NEAFFE, NEIF, NEIVE, NIEF.
PENIEPENIE n. (Spenser) a penny, also PENI.
SEINEseine n. A long net having floats attached at the top and sinkers (weights) at the bottom, used in shallow water…
seine v. (Transitive, intransitive) To use a seine, to fish with a seine.
Seine prop.n. A river in northern France that flows through Paris for about 772 km (480 mi) to the English Channel near Le Havre.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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