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There are 4 ten-letter words containing D, 2I, O, P, R, S and U

DISRUPTIONdisruption n. An interruption to the regular flow or sequence of something.
disruption n. A continuing act of disorder.
disruption n. A breaking or bursting apart; a breach.
OPHIUROIDSophiuroids n. Plural of ophiuroid.
OPHIUROID n. a member of the Ophiura genus of brittle-stars or sand-stars, also OPHIURA, OPHIURAN, OPHIURID.
PERFIDIOUSperfidious adj. Of, pertaining to, or representing perfidy; disloyal to what should command one’s fidelity or allegiance.
PERFIDIOUS adj. characterized by faithlessness or disloyalty.
PRODIGIOUSprodigious adj. Very big in size or quantity; colossal, gigantic, huge.
prodigious adj. Extraordinarily amazing or exciting.
prodigious adj. Freakish; monstrous.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 13 words
  • Scrabble in French: 10 words
  • Scrabble in Spanish: 6 words
  • Scrabble in Italian: 8 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 10 words


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