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There are 12 fifteen-letter words containing D, E, F, N, R, S and 2T

ANTIFEDERALISTSantifederalists n. Plural of antifederalist.
anti-federalists n. Plural of anti-federalist.
ANTIFEDERALIST n. one who is opposed to federalism.
DEFENESTRATIONSdefenestrations n. Plural of defenestration.
DEFENESTRATION n. the act of throwing a thing or person out of a window.
DENITRIFICATORSdenitrificators n. Plural of denitrificator.
DENITRIFICATOR n. an agent that denitrifies.
DESERTIFICATIONdesertification n. The process by which a geographic region becomes a desert, resulting from natural changes in climate…
DESERTIFICATION n. a process of land degradation initiated by human activity, particularly in the zones along the margins of deserts.
DIFFERENTIATORSdifferentiators n. Plural of differentiator.
DIFFERENTIATOR n. someone who or that which differentiates.
DISAFFORESTMENTdisafforestment n. Disafforestation.
DISAFFORESTMENT n. the act of disafforesting.
DISFEATUREMENTSDISFEATUREMENT n. the act of disfeaturing.
DISFORESTATIONSdisforestations n. Plural of disforestation.
DISFORESTATION n. the act of disforesting.
DISTRUSTFULNESSdistrustfulness n. The state or quality of being distrustful or doubtful; distrust; mistrust.
DISTRUSTFUL n. having or showing distrust.
INDIFFERENTISTSindifferentists n. Plural of indifferentist.
INDIFFERENTIST n. an exponent of indifferentism.
INTERSTRATIFIEDinterstratified adj. Stratified with two alternating types of strata.
INTERSTRATIFY v. to create strata between.
SOFTHEARTEDNESSsoftheartedness n. The state or condition of being softhearted; sentimental tenderness.
soft-heartedness n. Alternative form of softheartedness.
SOFTHEARTEDNESS n. the state of being softhearted.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 62 words
  • Scrabble in French: 16 words
  • Scrabble in Spanish: 5 words
  • Scrabble in Italian: 23 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 3 words


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