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There are 20 twelve-letter words containing D, 2E, H, N, 2R and S

DYSMENORRHEAdysmenorrhea n. (Medicine) Painful menstruation (menstrual#Adjective pain), viewed as a symptom#Noun in any of various disorders.
dysmenorrhea n. (Medicine) Painful menstruation (menstrual#Adjective pain), viewed as a disorder#Noun in its own right…
DYSMENORRHEA n. painful menstruation, also DYSMENORRHOEA.
HANDKERCHERShandkerchers n. Plural of handkercher.
HANDKERCHER n. a handkerchief, also HANDKERCHIEF.
HEADSHRINKERheadshrinker n. Alternative form of head-shrinker.
head-shrinker n. (Slang) A psychiatrist or psychotherapist; a shrink.
head-shrinker n. (Literally) One who shrinks heads, as previously done by some Amazon tribes.
HORRIDNESSEShorridnesses n. Plural of horridness.
HORRIDNESS n. the quality of being horrid.
MERCHANDISERmerchandiser n. A trader, seller or merchant, especially in the retail trade.
merchandiser n. An arcade machine which dispenses prizes to winners.
MERCHANDISER n. one who sells merchandise, also MERCHANDIZER.
NETHERWORLDSnetherworlds n. Plural of netherworld.
nether␣worlds n. Plural of nether world (alternative spelling of netherworlds).
NETHERWORLD n. the world of the dead; Hades; the lower depths of society.
NORTHERNISEDnorthernised v. Simple past tense and past participle of northernise.
NORTHERNISE v. to make northern, also NORTHERNIZE.
PHILANDERERSphilanderers n. Plural of philanderer.
PHILANDERER n. one who philanders.
RECHRISTENEDrechristened v. Simple past tense and past participle of rechristen.
RECHRISTEN v. to christen again.
REPREHENDERSreprehenders n. Plural of reprehender.
REPREHENDER n. one who reprehends.
SANDCHERRIESsand␣cherries n. Plural of sand cherry.
SHARPBENDERSSHARPBENDER n. an organization that has been underperforming its competitors but suddenly becomes more successful.
SUPERHARDENSsuperhardens v. Third-person singular simple present indicative form of superharden.
SUPERHARDEN v. to harden to extremes.
TETRAHEDRONStetrahedrons n. Plural of tetrahedron.
TETRAHEDRON n. a polyhedron that has four faces.
UNDERBREATHSunderbreaths n. Plural of underbreath.
UNDERBREATH n. subdued voice; rumour.
UNDERBRUSHEDunderbrushed v. Simple past tense and past participle of underbrush.
UNDERBRUSH v. to clear of underbrush.
UNDERBRUSHESunderbrushes n. Plural of underbrush.
UNDERBRUSH n. shrubs, small trees, and the like, in a wood or forest, growing beneath large trees.
UNDERCHARGESundercharges v. Third-person singular simple present indicative form of undercharge.
UNDERCHARGE v. to charge too little.
UNDERSHERIFFundersheriff n. In certain jurisdictions, a deputy sheriff; second in command to a sheriff.
UNDERSHERIFF n. one below the rank of sheriff.
UNDERSHIRTEDundershirted adj. Wearing an undershirt.
UNDERSHIRTED adj. wearing an undershirt.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 90 words
  • Scrabble in French: 22 words
  • Scrabble in Spanish: 41 words
  • Scrabble in Italian: 3 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 1 word


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