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There are 19 words containing 2D, 2E, I, O and 2T

DECOMMITTEDdecommitted v. Simple past tense and past participle of decommit.
DECOMMIT v. to withdraw from a commitment.
DECONTAMINATEDdecontaminated v. Simple past tense and past participle of decontaminate.
DECONTAMINATE v. to rid of contamination.
DECORTICATEDdecorticated adj. Having had the cortex removed.
decorticated v. Simple past tense and past participle of decorticate.
DECORTICATE v. to remove the bark, husk or peel of.
DEMOTIVATEDdemotivated v. Simple past tense and past participle of demotivate.
demotivated adj. Deprived or showing a decrease in motivation.
DEMOTIVATE v. to remove motivation from.
DETERIORATEDdeteriorated v. Simple past tense and past participle of deteriorate.
DETERIORATE v. to make inferior in quality or value.
DETOXICATEDdetoxicated v. Simple past tense and past participle of detoxicate.
DETOXICATE v. to rid of a poison or the effects of it.
DISCONTENTEDdiscontented adj. Experiencing discontent, dissatisfaction.
discontented adj. Of or pertaining to discontent.
DISCONTENT v. to make discontented.
DISCONTENTEDLYdiscontentedly adv. In a discontented manner.
DISCONTENTED adv. DISCONTENT, to make discontented.
DISORIENTATEDdisorientated v. Simple past tense and past participle of disorientate.
DISORIENTATE v. to cause to lose a sense of direction.
DISTORTEDNESSdistortedness n. The quality of being distorted.
DISTORTEDNESS n. the state of being distorted.
DISTORTEDNESSESDISTORTEDNESS n. the state of being distorted.
DOMESTICATEDdomesticated v. Simple past tense and past participle of domesticate.
domesticated adj. (Of an animal or a plant, especially a pet) selectively bred to live with or around humans.
DOMESTICATE v. to bring into domestic use.
OVERMULTITUDEDOVERMULTITUDE v. (Milton) to outnumber.
PERIODONTITIDESperiodontitides n. Plural of periodontitis.
RETRODICTEDretrodicted v. Simple past tense and past participle of retrodict.
RETRODICT v. to utilize present information or ideas to infer or explain (a past event or state of affairs).
TENDONITIDEStendonitides n. Plural of tendonitis.
TENDONITIS n. inflammation of a tendon, also TENDINITIS.
TRIETHIODIDEtriethiodide n. (Organic chemistry) Any compound containing three ethiodide groups.
triethiodide n. (Organic chemistry) Any compound containing three ethylammonium iodide groups.
TRIETHIODIDE n. as in gallamine triethiodide, a neuromuscular blocking agent used in anaesthesia.
TRIETHIODIDESTRIETHIODIDE n. as in gallamine triethiodide, a neuromuscular blocking agent used in anaesthesia.
UNDOMESTICATEDundomesticated adj. Not domesticated.
UNDOMESTICATE v. to make not domesticated.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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