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There are 10 words containing 2D, 4E, F and R

DEDIFFERENTIATEdedifferentiate v. To lose or reverse differentiation.
DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DEFENESTRATEDdefenestrated v. Simple past tense and past participle of defenestrate.
DEFENESTRATE v. to throw out of a window.
DEFORMEDNESSESDEFORMEDNESS n. the state of being deformed.
ENFREEDOMEDenfreedomed v. Simple past tense and past participle of enfreedom.
ENFREEDOM v. (Shakespeare) to set free, also ENFREE.
FEATHERBEDDEDfeatherbedded v. Simple past tense and past participle of featherbed.
feather-bedded v. Simple past tense and past participle of feather-bed.
FEATHERBED v. to pamper; to protect (an industry, workers, etc.) by such practices as overmanning in order to save jobs.
FEATHEREDGEDfeatheredged v. Simple past tense and past participle of featheredge.
feather␣edged v. Simple past tense and past participle of feather edge.
FEATHEREDGE v. to provide with feathered edge.
FEATHERHEADEDfeatherheaded adj. Alternative form of feather-headed.
feather-headed adj. (Colloquial) giddy; frivolous; foolish.
FEATHERHEADED adj. foolish, empty-headed.
FREEHANDEDNESSfreehandedness n. The quality or state of being freehanded.
free-handedness n. Alternative form of freehandedness.
FREEHANDED n. openhanded, liberal.
REDEFEATEDredefeated v. Simple past tense and past participle of redefeat.
REDEFEAT v. to defeat again.
REDEFECTEDredefected v. Simple past tense and past participle of redefect.
re-defected v. Simple past tense and past participle of re-defect.
REDEFECT v. to defect again.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 176 words
  • Scrabble in French: 29 words
  • Scrabble in Spanish: 28 words
  • Scrabble in Italian: 58 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 1 word


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