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There are 12 words containing D, O, 2P and 3S

PREDISPOSESpredisposes v. Third-person singular simple present indicative form of predispose.
PREDISPOSE v. to dispose in advance.
SPHENOPSIDSsphenopsids n. Plural of sphenopsid.
SPHENOPSID n. any of a class of tracheophyte with jointed ribbed stems.
PREDISPOSALSPREDISPOSAL n. disposal in advance.
PREPOSSESSEDprepossessed v. Simple past tense and past participle of prepossess.
prepossessed adj. Showing bias or partiality.
PREPOSSESS v. to bias or prejudice favourably; to impress.
PSEUDOSCOPESpseudoscopes n. Plural of pseudoscope.
PSEUDOSCOPE n. an instrument producing images in reversed relief.
HYPOSPADIASEShypospadiases n. Plural of hypospadias.
hypospadiases n. Plural of hypospadiasis.
HYPOSPADIAS n. a malformation of the penis.
DEIPNOSOPHISTSdeipnosophists n. Plural of deipnosophist.
DEIPNOSOPHIST n. a person skilled in dinner conversation.
POSTDEPRESSIONpostdepression adj. After an economic depression.
POSTDEPRESSION adj. after a depression.
UNPREPOSSESSEDunprepossessed adj. (Rare) Not prepossessed; unbiased.
UNPREPOSSESSED adj. not prepossessed.
PREDISPOSITIONSpredispositions n. Plural of predisposition.
PREDISPOSITION n. an inclination.
PSEUDOMORPHISMSpseudomorphisms n. Plural of pseudomorphism.
PSEUDOMORPHISM n. the state of being pseudomorphic.
PSEUDOSCORPIONSpseudoscorpions n. Plural of pseudoscorpion.
PSEUDOSCORPION n. any of various small arachnids of the order Pseudoscorpiones, resembling a scorpion but tailless, and found in soil, leaf litter, bark, etc.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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