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There are 12 words containing D, O, 2P and 3S

DEIPNOSOPHISTSdeipnosophists n. Plural of deipnosophist.
DEIPNOSOPHIST n. a person skilled in dinner conversation.
HYPOSPADIASEShypospadiases n. Plural of hypospadias.
hypospadiases n. Plural of hypospadiasis.
HYPOSPADIAS n. a malformation of the penis.
POSTDEPRESSIONpostdepression adj. After an economic depression.
POSTDEPRESSION adj. after a depression.
PREDISPOSALSPREDISPOSAL n. disposal in advance.
PREDISPOSESpredisposes v. Third-person singular simple present indicative form of predispose.
PREDISPOSE v. to dispose in advance.
PREDISPOSITIONSpredispositions n. Plural of predisposition.
PREDISPOSITION n. an inclination.
PREPOSSESSEDprepossessed v. Simple past tense and past participle of prepossess.
prepossessed adj. Showing bias or partiality.
PREPOSSESS v. to bias or prejudice favourably; to impress.
PSEUDOMORPHISMSpseudomorphisms n. Plural of pseudomorphism.
PSEUDOMORPHISM n. the state of being pseudomorphic.
PSEUDOSCOPESpseudoscopes n. Plural of pseudoscope.
PSEUDOSCOPE n. an instrument producing images in reversed relief.
PSEUDOSCORPIONSpseudoscorpions n. Plural of pseudoscorpion.
PSEUDOSCORPION n. any of various small arachnids of the order Pseudoscorpiones, resembling a scorpion but tailless, and found in soil, leaf litter, bark, etc.
SPHENOPSIDSsphenopsids n. Plural of sphenopsid.
SPHENOPSID n. any of a class of tracheophyte with jointed ribbed stems.
UNPREPOSSESSEDunprepossessed adj. (Rare) Not prepossessed; unbiased.
UNPREPOSSESSED adj. not prepossessed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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