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There are 15 words containing D, G, R, 2S and 2U

SOURDOUGHSsourdoughs n. Plural of sourdough.
sour-doughs n. Plural of sour-dough.
sour␣doughs n. Plural of sour dough.
DEMIURGUSESdemiurguses n. Plural of demiurgus.
DEMIURGUS n. (Greek) an inferior god who created the world; a creative power or spirit, also DEMIURGE.
GUARDHOUSESguardhouses n. Plural of guardhouse.
GUARDHOUSE n. a building for the accommodation of a military guard, and where prisoners are confined.
GROUNDBURSTSgroundbursts n. Plural of groundburst.
GROUNDBURST n. the detonation of a nuclear warhead at ground level.
SURROUNDINGSsurroundings n. Plural of surrounding.
surroundings n. The area surrounding someone or something, together with the objects and circumstances in the vicinity;…
surroundings n. (Physics) All parts of the universe that are not within the thermodynamic system of interest.
DESULFURISINGdesulfurising v. Present participle of desulfurise.
DESULFURISE v. to remove the sulfur from a compound, also DESULFURIZE, DESULPHURISE, DESULPHURIZE.
FUSSBUDGETIERFUSSBUDGETY adj. like a fussbudget, a person who fusses about unimportant things.
SCULDUGGERIESsculduggeries n. Plural of sculduggery.
SCULDUGGERY n. underhand dealing, trickery, also SKULDUGGERY, SKULLDUGGERY.
SKULDUGGERIESskulduggeries n. Plural of skulduggery.
SKULDUGGERY n. underhand dealing, trickery, also SCULDUGGERY, SKULLDUGGERY.
UNGUARDEDNESSunguardedness n. The state or condition of being unguarded.
UNGUARDEDNESS n. the state of being unguarded.
DESULPHURISINGdesulphurising v. Present participle of desulphurise.
DESULPHURISE v. to remove the sulphur from a compound, also DESULFURISE, DESULFURIZE, DESULPHURIZE.
GLUCURONIDASESglucuronidases n. Plural of glucuronidase.
GLUCURONIDASE n. an enzyme that hydrolyzes a glucuronide.
SKULLDUGGERIESskullduggeries n. Plural of skullduggery.
SKULLDUGGERY n. underhand dealing, trickery, also SCULDUGGERY, SKULDUGGERY.
UNGROUNDEDNESSungroundedness n. Quality of being ungrounded.
UNGROUNDEDNESS n. the state of being ungrounded.
UNGUARDEDNESSESunguardednesses n. Plural of unguardedness.
UNGUARDEDNESS n. the state of being unguarded.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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