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There are 20 words containing 2D, 2N, 2O and S

DESNOODINGDESNOOD v. to remove a turkey's snood to discourage cannibalism.
DICYNODONTSdicynodonts n. Plural of dicynodont.
DICYNODONT n. a fossil reptile with no teeth except for two in the upper jaw.
ENDODONTICSendodontics n. The branch of dentistry dealing with the dental pulp and root.
ENDODONTICS n. a branch of dentistry concerned with diseases of the pulp.
ENDODONTISTendodontist n. One who specializes in endodontics, a specialty of dentistry.
ENDODONTIST n. a practitioner of endodontics.
NOTODONTIDSnotodontids n. Plural of notodontid.
NOTODONTID n. a member of the Notodontidae genus of moths.
DECONDITIONSdeconditions v. Third-person singular simple present indicative form of decondition.
DECONDITION v. to cause extinction of (a conditioned response).
DOWNLOADINGSDOWNLOADING n. the act of obtaining data files from the Internet.
ENDODONTISTSendodontists n. Plural of endodontist.
ENDODONTIST n. a practitioner of endodontics.
LIRIODENDRONSliriodendrons n. Plural of liriodendron.
LIRIODENDRON n. the tulip tree.
PHILODENDRONSphilodendrons n. Plural of philodendron.
PHILODENDRON n. any of various aroid plants cultivated for their showy foliage.
RHODODENDRONSrhododendrons n. Plural of rhododendron.
RHODODENDRON n. any of a genus of widely cultivated shrubs and trees of the heath family.
UNDISHONOUREDundishonoured adj. Not dishonoured.
UNDISHONOURED adj. not dishonoured.
CONFOUNDEDNESSconfoundedness n. The state or quality of being confounded.
CONFOUNDEDNESS n. the state of being confounded.
ENDORADIOSONDEendoradiosonde n. A radiopill.
ENDORADIOSONDE n. a miniature battery-powered transmitter designed to be swallowed by the patient to send out information about a bodily function such as digestion.
UNCONSOLIDATEDunconsolidated adj. Not (yet) consolidated.
unconsolidated v. Simple past tense and past participle of unconsolidate.
UNCONSOLIDATED adj. loosely arranged.
ANDROMEDOTOXINSandromedotoxins n. Plural of andromedotoxin.
ANDROMEDOTOXIN n. a poisonous substance extracted from plants of the heath family and used in medicine to lower high blood pressure.
ANDROSTENEDIONEandrostenedione n. (Biochemistry, steroids) A steroid sex hormone C19H26O2 that is secreted by the testes, ovaries, and…
DISCOMMENDATIONdiscommendation n. (Archaic) blame; censure; reproach; shunning.
DISCOMMENDATION n. the act of discommending.
ENDORADIOSONDESendoradiosondes n. Plural of endoradiosonde.
ENDORADIOSONDE n. a miniature battery-powered transmitter designed to be swallowed by the patient to send out information about a bodily function such as digestion.
NONCONSOLIDATEDnonconsolidated adj. (Financial) Including the financial data of only the parent company.
NONCONSOLIDATED adj. not consolidated.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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