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There are 12 words containing 2D, E, N, P, S and Y

SPLENDIDLYsplendidly adv. In a splendid manner.
SPLENDID adv. magnificent.
DESPONDENCYdespondency n. The loss of hope or confidence; despair or dejection.
despondency n. A feeling of depression or disheartenment.
DESPONDENCY n. the state of being despondent, also DESPONDENCE.
HYPNOIDISEDHYPNOIDISE v. to put in the hypnoidal state, also HYPNOIDIZE.
PADDYMELONSpaddymelons n. Plural of paddymelon.
PADDYMELON n. (Native Australian) any of several small wallabies, also PADEMELON, PADYMELON.
DEHYPNOTISEDdehypnotised v. Simple past tense and past participle of dehypnotise.
DEHYPNOTISE v. to free from hypnosis, also DEHYPNOTIZE.
DENDROGLYPHSdendroglyphs n. Plural of dendroglyph.
DENDROGLYPH n. an ancient carving on a tree.
DESPONDENTLYdespondently adv. In a despondent manner.
DESPONDENT adv. feeling or showing extreme discouragement.
DESPONDINGLYdespondingly adv. In a desponding manner.
DESPONDING adv. hopeless.
UNDISPUTEDLYundisputedly adv. In a way, or to an extent, that is not disputed.
UNDISPUTED adv. not disputed.
SPONDYLITIDESspondylitides n. Plural of spondylitis.
SPONDYLITIS n. inflammation of the vertebra.
DISAPPOINTEDLYdisappointedly adv. In a disappointed manner.
DISAPPOINTED adv. DISAPPOINT, to fail to meet the expectation or hope of.
SIMPLEMINDEDLYsimplemindedly adv. In a simpleminded manner.
simple-mindedly adv. In a simple-minded manner. Lacking sophistication or intelligence.
SIMPLEMINDED adv. devoid of subtlety.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 395 words
  • Scrabble in French: 3 words
  • Scrabble in Spanish: 4 words
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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