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There are 16 words containing 2D, E, M, S and 2T

ADDITAMENTSadditaments n. Plural of additament.
ADDITAMENT n. a thing added or appended; a heraldic ornament.
DEMONSTRATEDdemonstrated v. Simple past tense and past participle of demonstrate.
DEMONSTRATE v. to show clearly.
DERMATITIDESdermatitides n. Plural of dermatitis.
DERMATITIS n. inflammation of the skin.
DOMESTICATEDdomesticated v. Simple past tense and past participle of domesticate.
domesticated adj. (Of an animal or a plant, especially a pet) selectively bred to live with or around humans.
DOMESTICATE v. to bring into domestic use.
MIDLATITUDESmidlatitudes n. Plural of midlatitude.
MIDLATITUDE n. a latitude in the temperate regions.
ADMINISTRATEDadministrated v. Simple past tense and past participle of administrate.
ADMINISTRATE v. to administer.
DESTIGMATIZEDdestigmatized v. Simple past tense and past participle of destigmatize.
DISEMBITTEREDdisembittered v. Simple past tense and past participle of disembitter.
DISEMBITTER v. to free from bitterness.
MASTOIDITIDESmastoiditides n. Plural of mastoiditis.
MASTOIDITIS n. inflammation of mastoid cells.
MITHRIDATISEDmithridatised v. Simple past tense and past participle of mithridatise.
MITHRIDATISE v. to acquire immunity to a poison acquired by taking gradually increased doses of it, also MITHRIDATIZE.
MULTISTRANDEDmultistranded adj. Composed of multiple strands.
MULTISTRANDED adj. having many strands.
UNDEMONSTRATEDundemonstrated adj. Not demonstrated.
UNDEMONSTRATED adj. not demonstrated.
UNDERESTIMATEDunderestimated v. Simple past tense and past participle of underestimate.
UNDERESTIMATE v. to estimate as being less than the actual size, quantity, or number.
UNDOMESTICATEDundomesticated adj. Not domesticated.
UNDOMESTICATE v. to make not domesticated.
DISINTERMEDIATEdisintermediate v. (Business, banking, finance) To carry out disintermediation.
MULTICANDIDATESSorry, definition not available.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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