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There are 18 words containing 2D, E, M, R and 2T

READMITTEDreadmitted v. Simple past tense and past participle of readmit.
READMIT v. to admit again.
PREADMITTEDpreadmitted v. Simple past tense and past participle of preadmit.
PREADMIT v. to admit beforehand.
DEMONSTRATEDdemonstrated v. Simple past tense and past participle of demonstrate.
DEMONSTRATE v. to show clearly.
DERMATITIDESdermatitides n. Plural of dermatitis.
DERMATITIS n. inflammation of the skin.
DETERMINATEDdeterminated adj. (Nonstandard) determined.
determinated adj. (Nonstandard) determinate.
DETERMINATE v. (Shakespeare) to determine.
PREMEDITATEDpremeditated v. Simple past tense and past participle of premeditate.
premeditated adj. Planned, considered, or estimated in advance; deliberate.
PREMEDITATE v. to think about and revolve in the mind beforehand.
ADMINISTRATEDadministrated v. Simple past tense and past participle of administrate.
ADMINISTRATE v. to administer.
DISEMBITTEREDdisembittered v. Simple past tense and past participle of disembitter.
DISEMBITTER v. to free from bitterness.
INTERMEDIATEDintermediated v. Simple past tense and past participle of intermediate.
INTERMEDIATE v. to mediate between.
MITHRIDATISEDmithridatised v. Simple past tense and past participle of mithridatise.
MITHRIDATISE v. to acquire immunity to a poison acquired by taking gradually increased doses of it, also MITHRIDATIZE.
MITHRIDATIZEDmithridatized v. Simple past tense and past participle of mithridatize.
MITHRIDATIZE v. to acquire immunity to a poison acquired by taking gradually increased doses of it, also MITHRIDATISE.
MULTISTRANDEDmultistranded adj. Composed of multiple strands.
MULTISTRANDED adj. having many strands.
OVERMULTITUDEDOVERMULTITUDE v. (Milton) to outnumber.
PREMEDITATEDLYpremeditatedly adv. In a premeditated manner.
PREMEDITATED adv. PREMEDITATE, to think about and revolve in the mind beforehand.
UNDEMONSTRATEDundemonstrated adj. Not demonstrated.
UNDEMONSTRATED adj. not demonstrated.
UNDERESTIMATEDunderestimated v. Simple past tense and past participle of underestimate.
UNDERESTIMATE v. to estimate as being less than the actual size, quantity, or number.
UNPREMEDITATEDunpremeditated adj. Performed, but not planned or thought out in advance; extemporaneous, but not unintentional.
UNPREMEDITATED adj. not premeditated.
DISINTERMEDIATEdisintermediate v. (Business, banking, finance) To carry out disintermediation.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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