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There are 12 words containing 2D, E, L, 2M and O

CHLAMYDOMONADESCHLAMYDOMONAS n. a member of the genus Chlamydomonas of (mainly freshwater) green algae.
DISCOMMENDABLEdiscommendable adj. Deserving disapprobation or blame.
DISCOMMENDABLE adj. that can be discommended.
LAMPADEDROMIESLAMPADEDROMY n. a foot race with lighted torches, esp. a relay race in which the torch is passed on, also LAMPADEPHORIA.
LAMPADEDROMYLAMPADEDROMY n. a foot race with lighted torches, esp. a relay race in which the torch is passed on, also LAMPADEPHORIA.
MEDDLESOMEmeddlesome adj. Characterised or marked by meddling; inclined or having a tendency to meddle or interfere in other people’s…
MEDDLESOME adj. given to meddling.
MEDDLESOMELYmeddlesomely adv. In a meddlesome manner.
MEDDLESOME adv. given to meddling.
MEDDLESOMENESSmeddlesomeness n. The qualities of being meddlesome; officiousness, intrusiveness.
MEDDLESOMENESS n. the state of being meddlesome.
MELODRAMATISEDmelodramatised v. Simple past tense and past participle of melodramatise.
MELODRAMATISE v. to make melodramatic, also MELODRAMATIZE.
MELODRAMATIZEDmelodramatized v. Simple past tense and past participle of melodramatize.
MELODRAMATIZE v. to make melodramatic, also MELODRAMATISE.
MIDDLEBROWISMmiddlebrowism n. Middlebrow attitudes generally.
MIDDLEBROWISM n. the state of being middlebrow.
MIDDLEBROWISMSMIDDLEBROWISM n. the state of being middlebrow.
MIDDLEMOSTmiddlemost adj. Nearest to the exact middle; midmost.
MIDDLEMOST adj. being in the middle, or nearest the middle, also MIDMOST.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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