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There are 12 words containing 2D, E, F, M, S and U

BEFUDDLEMENTSbefuddlements n. Plural of befuddlement.
BEFUDDLEMENT n. the state of being befuddled.
DEFRAUDMENTSdefraudments n. Plural of defraudment.
DEFRAUDMENT n. the act of defrauding.
DEHUMIDIFIERSdehumidifiers n. Plural of dehumidifier.
DEHUMIDIFIER n. an apparatus for reducing humidity.
DEHUMIDIFIESdehumidifies v. Third-person singular simple present indicative form of dehumidify.
DEHUMIDIFY v. to remove moisture from (as air).
DEMULSIFIEDdemulsified v. Simple past tense and past participle of demulsify.
DEMULSIFY v. to separate from an emulsion.
DIAMONDIFEROUSdiamondiferous adj. (Mineralogy) Yielding diamond.
DIAMONDIFEROUS adj. containing diamonds.
DUFFERDOMSDUFFERDOM n. being a duffer, also DUFFERISM.
DUMBFOUNDERSdumbfounders n. Plural of dumbfounder.
DUMBFOUNDER v. to strike dumb; to confuse with astonishment, also DUMBFOUND, DUMFOUND, DUMFOUNDER.
DUMFOUNDERSdumfounders v. Third-person singular simple present indicative form of dumfounder.
DUMFOUNDER v. to strike dumb; to confuse with astonishment, also DUMBFOUND, DUMBFOUNDER, DUMFOUND.
SULFADIMIDINEsulfadimidine n. (Pharmacology) A particular sulfonamide antibacterial agent.
SULFADIMIDINE n. a sulpha drug used in human and veterinary medicine.
SULFADIMIDINESSULFADIMIDINE n. a sulpha drug used in human and veterinary medicine.
UNDISCOMFITEDundiscomfited adj. Not discomfited.
UNDISCOMFITED adj. not discomfited.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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