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There are 18 words containing 2D, 2E, N and 2P

APPENDEDappended v. Simple past tense and past participle of append.
APPEND v. to add on to.
APPREHENDEDapprehended v. Simple past tense and past participle of apprehend.
apprehended adj. Taken; seized.
apprehended adj. Conceived; understood.
ENDOPEPTIDASEendopeptidase n. (Biochemistry) Any of a group of enzymes, such as trypsin, chymotrypsin, pepsin and elastase, which…
ENDOPEPTIDASE n. any of a group of enzymes that hydrolyze peptide bonds within the long chains of protein molecules.
ENDOPEPTIDASESendopeptidases n. Plural of endopeptidase.
ENDOPEPTIDASE n. any of a group of enzymes that hydrolyze peptide bonds within the long chains of protein molecules.
MISAPPREHENDEDmisapprehended v. Simple past tense and past participle of misapprehend.
misapprehended adj. Misunderstood.
MISAPPREHEND v. to apprehend wrongly.
PERPENDEDperpended v. Simple past tense and past participle of perpend.
PERPEND v. to weigh in the mind; to consider carefully.
PREPONDERATEDpreponderated v. Simple past tense and past participle of preponderate.
PREPONDERATE v. to surpass others in numbers, intensity, force, or prowess.
PROPENDEDpropended v. Simple past tense and past participle of propend.
PROPEND v. (Shakespeare) to have a tendency toward.
PSEUDOEPHEDRINEpseudoephedrine n. (Pharmacology) A sympathomimetic alkaloid commonly used as a decongestant; a chemical compound, an isomer…
PSEUDOEPHEDRINE n. a naturally occurring isomer of ephedrine, used in the form of its hydrochloride as a bronchodilator.
SANDPAPEREDsandpapered adj. Treated with sandpaper.
sandpapered v. Simple past tense and past participle of sandpaper.
SANDPAPER v. to smooth or polish with sandpaper.
UNAPPREHENDEDunapprehended adj. Not apprehended.
unapprehended adj. Not understood.
UNAPPREHENDED adj. not apprehended.
UNDERLAPPEDunderlapped v. Simple past tense and past participle of underlap.
UNDERLAP v. to extend partly under.
UNDERPEEPEDunderpeeped v. Simple past tense and past participle of underpeep.
UNDERPEEP v. (Shakespeare) to peep under.
UNDERPEOPLEDunderpeopled adj. Short of people; underpopulated.
UNDERPEOPLED adj. underpopulated.
UNDERPOPULATEDunderpopulated adj. Having an insufficient population for economic viability.
UNDERPOPULATED adj. having a lower density of population than is normal or desirable.
UNDERPREPAREDunderprepared adj. Not adequately prepared.
UNDERPREPARED adj. inadequately prepared.
UNDERPROPPEDunderpropped v. Simple past tense and past participle of underprop.
UNDERPROP v. to prop from beneath.
UNDERSUPPLIEDundersupplied v. Simple past tense and past participle of undersupply.
UNDERSUPPLY v. to supply too little.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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