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There are 19 words containing 2D, 2E, F, M and S

BEFUDDLEMENTSbefuddlements n. Plural of befuddlement.
BEFUDDLEMENT n. the state of being befuddled.
DEFEMINISEDdefeminised v. Simple past tense and past participle of defeminise.
DEFEMINISE v. to remove feminine characteristics from, also DEFEMINIZE.
DEFORMALISEDDEFORMALISE v. to make less formal, also DEFORMALIZE.
DEFORMEDNESSdeformedness n. (Obsolete, rare) The quality or state of being deformed.
DEFORMEDNESS n. the state of being deformed.
DEFORMEDNESSESDEFORMEDNESS n. the state of being deformed.
DEFRAUDMENTSdefraudments n. Plural of defraudment.
DEFRAUDMENT n. the act of defrauding.
DEHUMIDIFIERSdehumidifiers n. Plural of dehumidifier.
DEHUMIDIFIER n. an apparatus for reducing humidity.
DEHUMIDIFIESdehumidifies v. Third-person singular simple present indicative form of dehumidify.
DEHUMIDIFY v. to remove moisture from (as air).
DEMULSIFIEDdemulsified v. Simple past tense and past participle of demulsify.
DEMULSIFY v. to separate from an emulsion.
DEMYSTIFIEDdemystified v. Simple past tense and past participle of demystify.
DEMYSTIFY v. to remove the mystery from.
FORMALDEHYDESformaldehydes n. Plural of formaldehyde.
FORMALDEHYDE n. a formic aldehyde, formalin.
MIDFIELDERSmidfielders n. Plural of midfielder.
MIDFIELDER n. a player who plays in the midfield.
MISDEFINEDmisdefined v. Simple past tense and past participle of misdefine.
MISDEFINE v. to define wrongly.
MISFIELDEDmisfielded v. Simple past tense and past participle of misfield.
MISFIELD v. to field badly.
MISIDENTIFIEDmisidentified v. Simple past tense and past participle of misidentify.
misidentified adj. Identified incorrectly.
MISIDENTIFY v. to identify wrongly.
SEMIDEIFIEDsemideified adj. Regarded to some extent as a god.
SEMIDEIFY v. to make something partially a god.
SEMIFREDDIsemifreddi n. Plural of semifreddo.
SEMIFREDDO n. (Italian) a partially frozen Italian dessert similar to ice-cream.
SEMIFREDDOsemifreddo n. Any dessert eaten cold but not frozen.
SEMIFREDDO n. (Italian) a partially frozen Italian dessert similar to ice-cream.
SEMIFREDDOSsemifreddos n. Plural of semifreddo.
SEMIFREDDO n. (Italian) a partially frozen Italian dessert similar to ice-cream.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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