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There are 16 words containing 2D, 2E, 2F and R

AFFRENDEDAFFRENDED adj. (Spenser) reconciled.
DEDIFFERENTIATEdedifferentiate v. To lose or reverse differentiation.
DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DIFFEREDdiffered v. Simple past tense and past participle of differ.
DIFFER v. to be unlike.
DIFFERENCEDdifferenced v. Simple past tense and past participle of difference.
DIFFERENCE v. to make or perceive a difference between or in, also DIFFERENCY.
DIFFERENCIEDDIFFERENCY v. to make or perceive a difference in, also DIFFERENCE.
DIFFERENTIATEDdifferentiated v. Simple past tense and past participle of differentiate.
differentiated adj. (Biology, of a cell or tissue) That has taken on a specialized form and function.
DIFFERENTIATE v. to obtain the mathematical derivative of.
DISAFFORESTEDdisafforested v. Simple past tense and past participle of disafforest.
DISAFFOREST v. to clear of forest, also DISFOREST.
FOREFENDEDforefended v. Simple past tense and past participle of forefend.
FOREFEND v. to protect, also FORFEND.
FORFENDEDforfended v. Simple past tense and past participle of forfend.
FORFEND v. (archaic) to protect, also FOREFEND.
FURFURALDEHYDEfurfuraldehyde n. (Organic chemistry) furfural.
FURFURALDEHYDE n. a liquid obtained by heating bran with dilute sulphuric acid, also FURAL, FURFURAL, FURFUROL, FURFUROLE, FUROL, FUROLE.
FURFURALDEHYDESFURFURALDEHYDE n. a liquid obtained by heating bran with dilute sulphuric acid, also FURAL, FURFURAL, FURFUROL, FURFUROLE, FUROL, FUROLE.
INTERDIFFUSEDinterdiffused v. Simple past tense and past participle of interdiffuse.
interdiffused adj. Mutually diffused.
INTERDIFFUSE v. to diffuse between.
REOFFENDEDreoffended v. Simple past tense and past participle of reoffend.
REOFFEND v. to offend again.
UNDERFULFILLEDUNDERFULFILLED adj. not fully fulfilled.
UNDERSTAFFEDunderstaffed adj. Having an inadequate number of workers or assistants.
UNDERSTAFFED adj. inadequately staffed.
UNDIFFERENCEDundifferenced adj. (Heraldry) Not having a mark of difference.
UNDIFFERENCED adj. not differenced.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 175 words
  • Scrabble in French: 45 words
  • Scrabble in Spanish: no word
  • Scrabble in Italian: 139 words
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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