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There are 18 words containing 2D, 3E, G and M

DEFRAGMENTEDdefragmented v. Simple past tense and past participle of defragment.
DEFRAGMENT v. to run a program which reduces or eliminates the fragmentation of (a file or disk) by bringing together parts of files stored in separate locations to a single location on the disk.
DEGERMEDdegermed v. Simple past tense and past participle of degerm.
degermed adj. (Of a cereal grain etc) From which the germ has been removed.
DEGERM v. to remove germs from.
DELEGITIMATEDdelegitimated v. Simple past tense and past participle of delegitimate.
DELEGITIMISEDdelegitimised v. Simple past tense and past participle of delegitimise.
DELEGITIMISE v. to deprive of legitimacy.
DELEGITIMIZEDdelegitimized v. Simple past tense and past participle of delegitimize.
DELEGITIMIZE v. to deprive of legitimacy, also DELEGITIMISE.
DEMAGNETISEDdemagnetised v. Simple past tense and past participle of demagnetise.
DEMAGNETISE v. to remove the magnetic property from, also DEMAGNETIZE.
DEMAGNETIZEDdemagnetized v. Simple past tense and past participle of demagnetize.
demagnetized adj. From which all magnetism has been removed.
DEMAGNETIZE v. to deprive of magnetic properties, also DEMAGNETISE.
DEMANDINGNESSESDEMANDINGNESS n. the state of being demanding.
DEMERGEDdemerged v. Simple past tense and past participle of demerge.
DEMERGE v. to remove a division from a corporation, also DEMERGER.
DEMERGEREDdemergered v. Simple past tense and past participle of demerger.
DEMERGER v. to remove a division from a corporation, also DEMERGE.
DEMIGODDESSESdemigoddesses n. Plural of demigoddess.
DEMIGODDESS n. a half-goddess; a woman whose nature is partly divine, esp. a heroine fabled to be the offspring of a god and a mortal.
DEPHLEGMATEDdephlegmated v. Simple past tense and past participle of dephlegmate.
DEPHLEGMATE v. to distill something, such as alcohol.
DEPIGMENTEDdepigmented v. Simple past tense and past participle of depigment.
DEPIGMENT v. to take away or reduce the pigmentation in.
GERRYMANDEREDgerrymandered v. Simple past tense and past participle of gerrymander.
GERRYMANDER v. to rearrange (voting districts) in the interests of a particular party or candidate, also JERRYMANDER.
MADDENINGNESSESMADDENINGNESS n. the state of being maddening.
MISGENDEREDmisgendered v. Simple past tense and past participle of misgender.
MISGENDER v. to refer to (a person) using a pronoun or title that does not correspond with that person's gender identity.
MISGUIDEDNESSESmisguidednesses n. Plural of misguidedness.
MISGUIDEDNESS n. the state of being misguided.
SLEDGEHAMMEREDsledgehammered v. Simple past tense and past participle of sledgehammer.
SLEDGEHAMMER v. to strike with a sledgehammer.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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