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There are 11 words containing 2D, 3E and 2F

FOREFENDED	• forefended v. Simple past tense and past participle of forefend. • FOREFEND v. to protect, also FORFEND.
REOFFENDED	• reoffended v. Simple past tense and past participle of reoffend. • REOFFEND v. to offend again.
DIFFERENCED	• differenced v. Simple past tense and past participle of difference. • DIFFERENCE v. to make or perceive a difference between or in, also DIFFERENCY.
DIFFERENCIED	• DIFFERENCY v. to make or perceive a difference in, also DIFFERENCE.
DECAFFEINATED	• decaffeinated adj. From which caffeine has been removed (e.g. decaffeinated coffee). • DECAFFEINATE v. to remove caffeine from.
UNDIFFERENCED	• undifferenced adj. (Heraldry) Not having a mark of difference. • UNDIFFERENCED adj. not differenced.
DIFFERENTIATED	• differentiated v. Simple past tense and past participle of differentiate. • differentiated adj. (Biology, of a cell or tissue) That has taken on a specialized form and function. • DIFFERENTIATE v. to obtain the mathematical derivative of.
DIFFUSEDNESSES	• DIFFUSEDNESS n. the state of being diffused.
DEDIFFERENTIATE	• dedifferentiate v. To lose or reverse differentiation. • DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DISAFFECTEDNESS	• disaffectedness n. The quality of being disaffected. • DISAFFECTEDNESS n. the state of being disaffected.
OFFHANDEDNESSES	• OFFHANDEDNESS n. the state of being offhanded.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 142 words
Scrabble in French: 37 words
Scrabble in Spanish: no word
Scrabble in Italian: 77 words
Scrabble in German: no word
Scrabble in Romanian: no word

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