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There are 12 fifteen-letter words containing 2D, 2E, 2O and S

ADENOIDECTOMIESadenoidectomies n. Plural of adenoidectomy.
ADENOIDECTOMY n. the surgical removal of the adenoids, also ADENECTOMY.
ANDROSTENEDIONEandrostenedione n. (Biochemistry, steroids) A steroid sex hormone C19H26O2 that is secreted by the testes, ovaries, and…
CHORDAMESODERMSCHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
CROTONALDEHYDEScrotonaldehydes n. Plural of crotonaldehyde.
CROTONALDEHYDE n. a pungent liquid aldehyde obtained by dehydration of aldol.
DEHYDRORETINOLSDEHYDRORETINOL n. vitamin A2.
DIHYDROCODEINESDIHYDROCODEINE n. a synthetic drug similar to codeine, used as an analgesic, an antidiarrhoeal, and to relieve coughing.
DISCOMBOBERATEDdiscomboberated v. Simple past tense and past participle of discomboberate.
DISCOMBOBERATE v. to throw into a state of confusion, also DISCOMBOBULATE.
ENDORADIOSONDESendoradiosondes n. Plural of endoradiosonde.
ENDORADIOSONDE n. a miniature battery-powered transmitter designed to be swallowed by the patient to send out information about a bodily function such as digestion.
HOBBLEDEHOYDOMSHOBBLEDEHOYDOM n. the state of being a hobbledehoy, an awkward young fellow, also HOBBLEDEHOYHOOD, HOBBLEDEHOYISM.
LEPIDODENDROIDSlepidodendroids n. Plural of lepidodendroid.
LEPIDODENDROID n. any of a genus of fossil trees.
OXIDOREDUCTASESoxidoreductases n. Plural of oxidoreductase.
OXIDOREDUCTASE n. an enzyme that catalyzes an oxidationreduction reaction.
PERIODONTITIDESperiodontitides n. Plural of periodontitis.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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